Myocardial Function in CAD Determined by Atrial Pacing

Analysis of left ventricular function by atrial pacing.

With the technique of right atrial pacing, left ventricular function was assessed in 21 normal subjects and in 13 patients with elevated left ventricular filling pressures. Since cardiac output does not change significantly with atrial pacing, the stroke volume decreases as an inverse function of the pacing rate. Stroke volume can thus be varied over a wide range, and by simultaneous measuremen...

Suppression of atrial fibrillation by atrial pacing.

BACKGROUND Atrial fibrillation (AF) is a common arrhythmia in patients with an implanted pacemaker, but the role of atrial pacing in preventing AF is still unclear. METHODS AND RESULTS Sixty-six patients (67.8+/-12.1 years) were enrolled: 54 with sick sinus syndrome (SSS), 11 with atrioventricular blocks (AVB), and 1 with SSS and AVB. The prevalence of AF was investigated. In 22 patients with...

Myocardial FFA metabolism during rest and atrial pacing in humans.

There is limited in vivo data in humans evaluating myocardial fat utilization during increased heart work. This study was done to determine myocardial free fatty acid (FFA) metabolism during rest and atrial pacing, which increases cardiac work without changing arterial substrate concentration. We studied seven healthy men and women (age = 49.7 +/- 3.9 yr, BMI = 23.4 +/- 1.1 kg/m(2), Vo(2max) = ...

Sequential alterations in myocardial lactate metaboli, S-T segments, and left ventricular function during angina induced by atrial pacing.

Sequential Alterations in Myocardial Lactate Metabolism , S - T Segments , and Left Ventricular Function During Angina Induced by Atrial Pacing

Myocardial lactate metabolism was monitored before, during, and after a period of atrial pacing with a continuous automated sampling technic. The electrocardiogram was recorded, and left ventricular function was evaluated by relating left ventricular enddiastolic pressure to left ventricular stroke work. Seventeen of 21 patients with coronary artery disease experienced angina during pacing, and...